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Pulmonary Medicine

The Pulmonary Medicine Conference is moderated by E. Neil Schachter, M.D., & Dr. Maurice Hexter Professor of Medicine at the Mount Sinai School of Medicine.

This conference may include discussion of commercial products and services.

The opinions expressed herein are those of the authors and do not necessarily represent the views of the sponsor or its publisher. Please review complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

Cystic Fibrosis -- No Longer Just a Disease of Pediatric Medicine

Cystic fibrosis (CF) is an autosomal recessive disease caused by genetic mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. At the cellular level, the CFTR protein is an anion channel normally present in the epithelial membrane of many cells. A dysfunctional or deficiency in the CFTR protein results in abnormal ion gradients, especially in chloride, and bicarbonate ions. The downstream effects of the abnormal ion gradients include dehydration on the airway surface due to an excess of sodium and
Authors: Arindam Singha, M.D., and Stephen E. Kirkby, M.D.
Estimated Time: 1 Hour
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E. Neil Schachter, M.D

Pulmonary Medicine

Dr. Neil Schachter, Cyberounds® Pulmonary Medicine moderator, is Dr. Maurice Hexter Professor of Medicine and Professor of Community Medicine at the Mount Sinai School of Medicine, where he is also the Associate Director of the Pulmonary Division. After studying mathematics at Columbia, he received his M.D. from NYU and completed postgraduate medical training at Bellevue Hospital. Before coming to Mt. Sinai, Neil was an Associate Professor of Medicine, Yale University School of Medicine. He has been the editor of several professional journals, written nearly 200 original peer-reviewed papers and has also authored/edited several textbooks, including Respiratory Pharmacology and the NAMDRC Handbook. An authority on byssinosis and an advocate for clean indoor air, Neil's current research focuses on the treatment of asthma and chronic bronchitis.

Within the past 12 months, Dr. Schachter has received grant research/support from GlaxoSmithKline and been on the Speakers Bureau for AstraZeneca, GlaxoSmithKline and Novartis.

Last Update: 2/21/2021

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More Pulmonary Medicine Courses

Asthma Management: A Multi-Faceted Approach

This presentation may include discussion of commercial products and services. Based on national survey data, 24.6 million people report a diagnosis of asthma in the United States, representing approximately 7.7% of adults and 9.6% of children. Certain populations including women, blacks and the poor are disproportionately affected. The direct and indirect costs related to adult asthma care in the United States were estimated to
Authors: Cathy G. Benninger, R.N., M.S., C.N.P., and Jennifer W. McCallister, M.D.
Estimated Time: 1 Hour
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Idiopathic Pulmonary Fibrosis

A competitive, interactive game format that will discuss the essentials of the management of idiopathic pulmonary fibrosis. This presentation may include discussion of commercial products and services. Table 1. Clinical Strategies for the Improvement of Asthma Control. Identify and manage co-morbid conditions which affect asthma control Source: based on the four key components of asthma management as outlined in the current National Heart, Lung, and Blood Institute (NHLBI) National Asthma Education and
Authors: Ganesh Raghu, M.D., and Samuel G. Rayner, M.D.
Estimated Time: 2 Hours
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The Role of Matrix Metalloproteinases (MMPs) in COPD

Though the pathophysiology of chronic bronchitis and emphysema is distinct, there are common processes that are linked to their development. For one, both syndromes are caused by chronic exposure to cigarette smoke, which generates a robust inflammatory response in the lung that results in a marked increase in proteases within the lung. Animal and human studies indicate that the presence of these proteases is a critical factor in the development of these diseases. In chronic bronchitis,
Authors: Robert Foronjy, M.D., and Jeanine D'Armiento, M.D., Ph.D.
Estimated Time: 1 Hour
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Acute Lung Injury and the Acute Respiratory Distress Syndrome

Acute lung injury (ALI) and its more severe manifestation, the acute respiratory distress syndrome (ARDS), are among the most common causes of acute hypoxemic respiratory failure in the intensive care unit (ICU). ALI complicates many medical and surgical conditions and represents a complex pathophysiologic sequela to a variety of different pulmonary and extrapulmonary insults. Initially described in the 1960s, ARDS is characterized by refractory hypoxemia, diffuse pulmonary infiltrates and decreased lung compliance. ALI and ARDS both represent
Authors: Chirag V. Shah, M.D., M.S., and Jason D. Christie, M.D., M.S.
Estimated Time: 1 Hour
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The Diagnosis and Management of Venous Thromboembolism

The differential diagnosis for acute PE is broad and includes a number of cardiopulmonary diseases and, occasionally, intra-abdominal processes may be mimicked by PE. Hypoxemia is extremely common but not always present in acute PE. The diagnostic utility of plasma measurements of circulating D-dimer (a specific derivative of cross-linked fibrin) has been extensively evaluated in patients with PE. A number of D-dimer assays are available, and the sensitivity and specificity of these assays vary. A positive D-dimer test means that
Authors: Victor F. Tapson, M.D.
Estimated Time: 1 Hour
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Idiopathic Pulmonary Fibrosis

Drs. Collard and King will discuss the unapproved and investigational use of cyclophosphamide, azathioprine, acetylcysteine, interferon gamma 1b, bosentan, pirfenidone and warfarin for the treatment of idiopathic pulmonary fibrosis. Case Report A 65-year-old man presents with shortness of breath and cough. Over the last six months he has had increasing breathlessness with exertion. He has a dry cough that is worse with exertion. He is a
Authors: Harold R. Collard, M.D., and Talmadge E. King, Jr., M.D.
Estimated Time: 1 Hour
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