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Genetic Basis of COVID-19 Susceptibility and Severity

The emergence of the second Sarbecovirus in the 21st century has led to a pandemic that has disrupted human society in an unprecedented mode in recent history. More than 80...

Course Authors

Cleo Anastassopoulou, Ph.D., and Athanasios Tsakris, M.D., Ph.D., F.R.C.Path.

Dr. Anastassopoulou is an Associate Professor of Medical Microbiology at the Laboratory of Microbiology of the National and Kapodistrian University of Athens Medical School, Athens, Greece; Dr. Tsakris is a Professor of Clinical Microbiology and the Director of the Department of Microbiology of the National and Kapodistrian University of Athens Medical School, Athens, Greece.

Within the past 12 months, Drs. Anastassopoulou and Tsakris have nothing to disclose relevant to this activity.

Albert Einstein College of Medicine – Montefiore Medical Center CCPD staff and interMDnet staff have nothing to disclose relevant to this activity.

Estimated time to complete: 1 hour(s).

Albert Einstein College of Medicine – Montefiore Medical Center designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

In support of improving patient care, this activity has been planned and implemented by Albert Einstein College of Medicine-Montefiore Medical Center and InterMDnet. Albert Einstein College of Medicine – Montefiore Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

 
Learning Objectives

Upon completion of this Cyberounds®, you should be able to:

  • List and discuss genetic factors potentially associated with differing susceptibility to COVID-19;

  • Discuss gene variants and relevant biological mechanisms that are important at different disease stages as well as points of potential pharmaceutic intervention;

  • List and discuss genetic factors potentially associated with severe COVID-19;

  • Explain why the disease course is typically more severe in males and benign in children.

 

TERMS AND CONDITIONS

The opinions expressed herein are those of the author(s) and do not necessarily represent the views of Einstein-Montefiore or InterMDnet. Please review complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

 

Please click below to accept the terms of this CME activity

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