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Psychiatry/Neuroscience

The Psychiatry/Neuroscience Conference was moderated by Bruce S. McEwen, Ph.D., Professor and Head of the Harold and Margaret Milliken Hatch Laboratory of Neuroendocrinology at The Rockefeller University.

This conference may include discussion of commercial products and services.

The opinions expressed herein are those of the authors and do not necessarily represent the views of the sponsor or its publisher. Please review complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

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Emerging Research on the Use of Psychedelics in the Treatment of Mental Illness

In the last 30 years, revived interest in the application of psychedelic compounds in psychiatry has created a huge body of scientific knowledge on the pharmacological and therapeutic action of… these compounds.
Authors: Danilo De Gregorio, PharmD, Ph.D.
Estimated Time: 1 Hour
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The Impact of COVID-19 on Mental Health

The coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization (W.H.O.) on March 11, 2020. China was the first country that identified the novel… coronavirus as the cause of the pandemic. Globally, as of May 25, 2020, the number of confirmed cases was 5,525,299, the number of deaths was 347,110 and the number of recovered cases was 2,316,127. The challenges of COVID-19 pandemic include the following issues: modified lifestyle due to lockdown and…
Authors: Roger Ho M.D., F.R.C.Psych., F.R.C.P.C., and Cyrus Ho M.B.B.S., M.R.C.Psych.
Estimated Time: 1 Hour
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Molecular Mechanisms of Cognitive Deficits in Schizophrenia

Schizophrenia is a severe mental disorder characterized by three main symptom domains: positive, negative and cognitive. While positive symptoms such as hallucinations and delusions are largely responsive to antipsychotic… medication, negative symptoms like anhedonia, and cognitive symptoms such as memory and attentional deficits, constitute a major unmet therapeutic need. Cognitive symptoms, in particular, have been the focus of substantial on-going clinical and preclinical research as cognitive impairment is highly predictive of long-term functional outcome in patients. …
Authors: Sarah Canetta, Ph.D., and Christoph Kellendonk, Ph.D.
Estimated Time: 1 Hour
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PTSD: Current Therapies

Childhood abuse, motor vehicle accidents, assault, and other psychological traumas and stressors represent a major public health problem in our society today. Psychological trauma, defined as threat to life or… integrity of yourself or someone close to you, affects over half of the U.S. population at some time in their lives. Childhood sexual abuse alone affects 16% of women (about 40 million) in the U.S.A. The most common cause of post traumatic stress disorder (PTSD) in women is…
Authors: J. Douglas Bremner, M.D.
Estimated Time: 1 Hour
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Current and Emerging Therapies for Relapsing-Remitting Multiple Sclerosis

This presentation may include discussion of commercial products and services. Dr. Miller will discuss unapproved therapies for MS including daclizumab, ocrelizumab, sphingosine-1-phosphate receptor molecules and ofatumumab. The modern era… of disease modifying therapy (DMT) in multiple sclerosis (MS) began in 1993 with the introduction of interferon beta-1b for the treatment of relapsing-remitting multiple sclerosis (RMMS). Since then, the U.S. Food and Drug Administration (FDA) has approved eight new unique therapeutic agents (actually nine products). In other parts…
Authors: Aaron Miller, M.D..
Estimated Time: 1 Hour
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Glial Cells

Astrocyte: Astrocytes are a type of non-neuronal cell in the central nervous system that exhibit a wide variety of cellular properties and shapes. These cells are involved in… a broad range of functions in disease and normal brain function. Microglia: Microglia are the immune system cells of the central nervous system, but they also help remodel synapses in response to neural activity. Oligodendrocyte: Oligodendrocytes form the multi-laminar myelin electrical insulation on axons in the…
Authors: R. Douglas Fields, Ph.D.
Estimated Time: 1 Hour
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The Management of Major Depression During Pregnancy

Susan has a history of severe recurrent depressive episodes with debilitating panic attacks beginning at age 14. She has been tried on all currently available SSRI medications, as well… as buproprion, mirtazapine and serezone. She has been successfully treated with paroxetine for the last three years and was either unable to tolerate or did not respond to the previous medication trials. She presents asking for treatment advice during pregnancy. How should her psychiatrist approach weighing the risks and…
Authors: Jennifer L. Payne, M.D.
Estimated Time: 1 Hour
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