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Rheumatology

The Rheumatology Conference is moderated by Peter Barland, M.D., Professor of Medicine at Albert Einstein College of Medicine.

This conference may include discussion of commercial products and services.

The opinions expressed herein are those of the authors and do not necessarily represent the views of the sponsor or its publisher. Please review complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

Treatment of Idiopathic Inflammatory Myopathy

Other than glucocorticoids and Acthar, the FDA has not approved any medications for the treatment of myositis. The idiopathic inflammatory myopathies (IIMs) are a group of heterogeneous, systemic rheumatic diseases that include adult polymyositis (PM), adult dermatomyositis (DM), myositis associated with other systemic autoimmune rheumatic diseases or cancer, juvenile myositis (juvenile dermatomyositis and juvenile polymyositis), inclusion body myositis (IBM) and necrotizing autoimmune myopathy. Because of their low incidence and prevalence, their variable clinical phenotypes and the small number of randomized,
Authors: Siamak Moghadam-Kia, M.D., Rohit Aggarwal, M.D. and Chester V. Oddis, M.D.
Estimated Time: 1 Hour
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Peter Barland, M.D.

Rheumatology

Peter Barland, M.D., Cyberounds® Rheumatology moderator, is Professor Emeritus, Department of Medicine (Rheumatology) at the Albert Einstein College of Medicine and the Director of Rheumatology for Montefiore Hospital in New York. He is also the director of Montefiore's Immunodiagnostic Laboratory. A graduate of Einstein, where he also trained, Peter was the recipient of the Arthritis Foundation's four year Research Training Fellowship. In recognition of his contributions to rheumatology, the Arthritis Foundation (New York Chapter) honored Dr. Barland in 1996 with its prestigious Charles M. Plotz Award.

Within the past 12 months, Dr. Barland reports no comercial conflict of interest.

Last Update: 2/21/2021

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More Rheumatology Courses

Idiopathic Inflammatory Myopathies: A 2016 Update

Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of autoimmune diseases, primarily affecting the skeletal muscles, which cause predominant proximal muscle weakness. The four main types of IIM are dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM) and a relative newcomer — immune mediated necrotizing myopathy (IMNM). The diagnosis of IIM typically begins with a careful assessment of the pattern of weakness, electromyography, MRI of the muscles when available and muscle biopsy, particularly in cases when a diagnostic skin rash
Authors: Julie J. Paik, M.D.. M.H.S. and Lisa Christopher-Stine, M.D., M.P.H.
Estimated Time: 1 Hour
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The Current Treatment of Lupus Nephritis

Lupus nephritis (LN) is a dreaded complication of systemic lupus erythematosus (SLE). One in six patients with SLE will have evidence of kidney involvement at the time of diagnosis and at least 40-75% patients will develop nephritis in the course of their SLE. Lupus nephritis continues to significantly affect morbidity and mortality. Both in the U.S. and in Europe, non-Caucasians have increased rates of nephritis. In the U.S., risk factors for progression to end-stage renal
Authors: Saakshi Khattri, M.D., and Peter Barland, M.D
Estimated Time: 1 Hour
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Palindromic Rheumatism

A 40-year-old female presents with a complaint of right knee pain and swelling for two days. Her symptoms started suddenly. All her other joints are normal. She has been having similar problems with arthritis for 20 years, when she noticed her first attack in a shoulder joint. The frequency of attacks has increased with age and most recently she has had approximately 10 to 15 attacks per year. The attacks can last from a few hours to three days, are
Authors: Sahitya Mallipeddi, M.D., Raghu Maddela, M.D., and Peter Barland, M.D.
Estimated Time: 1 Hour
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Immunoglobulin G4-related Sclerosing Syndrome

Immunoglobulin G4-related sclerosing syndrome (IgG4 RSS) is a newly recognized systemic clinicopathological entity. It is characterized by chronic inflammation and multiorgan involvement secondary to tissue infiltration with IgG4 secreting lymphoplasmocytic cells. It is also known for its dramatic response to steroids. The recent identification of IgG4 in the affected tissues of many chronic inflammatory syndromes has led to the recognition of a new clinicopathological entity — IgG4 RSS. Prior to the discovery of IgG4 RSS as a multiorgan disorder, many
Authors: Peguy Saad, M.D., and Peter Barland, M.D.
Estimated Time: 1 Hour
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Hemophagocytic Syndrome in Rheumatic Diseases

AH, a 23-year-old male, was admitted to our institution with five days of fever, abdominal pain and non-bloody diarrhea. He was febrile to 101.2°F, and his exam revealed a benign abdomen and no rash, lymphadenopathy or synovitis. He was found to be pancytopenic with a WBC of 2600/mm3, an absolute neutrophil count of 1700/mm3, a hemoglobin of 8.9 gm/dL and platelets of 22,000/mm3 with schistocytes seen on the peripheral blood smear. His International Normalized Ratio (INR) was increased at
Authors: Arlene Tan Tieng, M.D., Irene Blanco, M.D., and Peter Barland, M.D.
Estimated Time: 1 Hour
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A Critical Review of the Role of Vitamin D Deficiency in Autoimmune Diseases

Vitamin D receptor has been identified on various cells of the immune system including dendritic cells, mononuclear cells, antigen presenting cell and activated B and T lymphocytes. In vitro, addition of vitamin D was shown to decrease antibody production and secretion by B lymphocytes. It also has been shown to inhibit the differentiation of monocytes into immature dendritic cells. Vitamin D also plays a role in dendritic cell maturation and survival by maintaining the immature dendritic cell
Authors: Anna Broder, M.D., and Peter Barland, M.D.
Estimated Time: 1 Hour
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