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Endocrinology

Extracellular Calcium and Calcium Sensing Receptors: Evolving Perspectives

Extracellular calcium (Ca2+o) is an important divalent mineral ion critical for numerous physiological processes.
CME credit is no longer available for this conference.

Course Authors

Ogo I. Egbuna, M.D., M.Sc., and Edward M. Brown, M.D.

Release Date: 07/15/2008

 
Learning Objectives

Upon completion of this Cyberounds®, you should be able to:

  • Describe Ca2+o homeostasis, calcium-sensing receptors (CaSRs) and the role of the prototypical CaSR in Ca2+o homeostasis

  • Discuss recent advances in our understanding of the structure-function relationships and ligand binding sites of the CaSR

  • List the spectrum of mutations involving the CaSR that cause human disease and describe disorders arising from anti-CaSR autoantibodies

  • Discuss the actions of the CaSR in CaSR-expressing tissues in defending against both hypo- and hypercalcemia

  • Discuss the current and potential utility of CaSR-based therapeutics

  • Outline future directions in CaSR physiology and research.

 

TERMS AND CONDITIONS

This conference may include discussion of commercial products and services.

The opinions expressed herein are those of the authors and do not necessarily represent the views of the sponsor or its publisher. Please review complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

 

Please click below to accept the terms.

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