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Infections in Long-term Care Facilities:
Epidemiology, Diagnosis and Prevention
Lona Mody, M.D., M.Sc.

Dr. Mody is an Assistant Professor, University of Michigan Medical School, and Associate Director, Clinical Programs, at the Ann Arbor VA Geriatric Research Education and Clinical Center, Ann Arbor, Michigan.

Within the past 12 months, Dr. Mody reports no commercial conflicts of interest.


Release Date: 07/21/2009
Termination Date: 07/21/2012

Estimated time to complete: 1 hour(s).

Albert Einstein College of Medicine designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Albert Einstein College of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
 
Learning Objectives
Upon completion of this Cyberounds®, the participant should be able to:
  • Describe risk factors and epidemiology of common infections in long-term care facility residents
  • List diagnostic criteria for infections in patients with a paucity of symptoms
  • Implement strategies to prevent common infections in long-term care facility residents.

 

Healthcare delivery in the United States has evolved dramatically over the last two decades. Previously, healthcare occurred primarily in acute care facilities. Today, it is delivered in multiple settings including hospitals, sub-acute care, long-term care facilities (LCTFs) or nursing homes, rehabilitation, assisted living, home and outpatient settings.

Efforts to restrain healthcare costs have led to a reduced number of hospitalizations and shorter lengths of stay (with an associated increase in severity of illness and intensive care unit admissions), along with increased outpatient, home care and nursing home stays for older adults.(1) As a consequence, nursing homes and rehabilitation units are seeing sicker patients, who require more intense medical supervision and are more susceptible to infections and antimicrobial resistance (Table 1).

Table 1. Differences Between Acute Care Hospitals and Nursing Homes With Respect to Infection Management.

Characteristics Acute Care Hospitals Nursing Homes
Patient Population All ages Predominantly older adults
Overall Goals of patient care Acute care management, Disease recovery Predominantly chronic disease management with spurts of acute disease management, Functional recovery and stability
Length of stay Days, weeks Years
Physician visits Frequent, daily Infrequent, often monthly
Recognition of infection signs Physicians and nurses Nurses aides first, followed by nurses and physicians
Infection definition Based on physical findings as well as laboratory Based on physical findings with limited timely laboratory support
Resources for Infection Control Broad Very variable, inconsistent

Infections in LTCFs increase the mortality and morbidity of residents and lead to transfers to acute care hospitals. In fact, each year, a staggering 1.5-2.0 million infections occur in long-term care facilities, resulting in frequent hospital transfers and an estimated 1-2 billion dollars in hospital expenditures.(2)

Older adults over the age of 65 account for a disproportionate share of patients with infection-related hospitalizations in the U.S.(3) The hazards of the hospitalization of LTCF residents are numerous and include functional decline, delirium, pressure ulcers and adverse drug events (Figure 1). This Cyberounds® review highlights the epidemiology, diagnosis and prevention of common infections in the long-term care setting.

Figure 1. Pathway to Nursing Home Infections and Antimicrobial Resistance.

Figure1

Click here to view full image.

Q

A 72-year-old woman residing in a long-term care facility, who has advanced dementia, moderate functional loss and congestive heart failure, now presents with increasing cough, fever up to 100.6°F and increasing confusion. She states that she is seeing strange people entering and leaving her room. Her daughter confirms that this deterioration in mental status is new. On physical exam, her blood pressure is 101/40 mm Hg, pulse 125/min, respirations 26/min and pulse ox 84%. You decide to transfer her to the hospital for evaluation of fever and management.

What are the potential side effects of hospitalization in this population?

 
a. Delirium
b. Dementia
c. Adverse drug events
d. All of the above
e. A and C.
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Footnotes

1Jarvis WR. Infection control and changing health-care delivery systems. Emerg Infect Dis 2001;7:170-173.
2Smith PW, Bennett G, Bradley SF, Drinka P, Lautenbach E, Marx J, McGeer A, Mody L, Nicolle L, Richards C, Stevenson K. Infection prevention and control in long-term care facilities Infect Control Hosp Epidemiol 2008;29:785-814.
3Curns AT, Holman RC, Sejvar JJ, Owings MF, Schonberger LB. Infectious disease hospitalizations among older adults in the United States from 1990 through 2002. Arch Intern Med 205;165:2514-20.