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Oxygen Homeostasis in Health and Disease

Every nucleated cell in the body is capable of sensing a reduction in oxygen concentration and responding by activation of HIF-1.
CME credit is no longer available for this conference.

Course Authors

Gregg L. Semenza, M.D., Ph.D.

Release Date: 09/15/2007

 
Learning Objectives

Upon completion of this Cyberounds®, you should be able to:

  • Discuss the molecular mechanisms by which changes in cellular PO2 are sensed and transduced to changes in gene expression through the activity of HIF-1

  • Discuss the role of HIF-1 and its downstream gene products in mediating adaptive responses to tissue ischemia and relevant translational research

  • Discuss the role of HIF-1 in the pathogenesis of cancer and relevant translational research.

 

TERMS AND CONDITIONS

The opinions expressed herein are those of the authors and do not necessarily represent the views of the sponsor or its publisher. Please review complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.

 

Please click below to accept the terms.

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