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Protective and Damaging Effects of Mediators of Adaptation
CME credit is no longer available for this conference.
Bruce S. McEwen, Ph.D.

Dr. McEwen reports no conflict of interest.

This activity is made possible by an unrestricted educational grant from Forest Laboratories.

Release Date: 07/21/2004
Termination Date: 07/21/2007

Estimated time to complete: 1 hour(s).

Albert Einstein College of Medicine – Montefiore Medical Center designates this enduring material activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

In support of improving patient care, this activity has been planned and implemented by Albert Einstein College of Medicine-Montefiore Medical Center and InterMDnet. Albert Einstein College of Medicine – Montefiore Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Learning Objectives
Upon completion of this Cyberounds®, you should be able to:
  • Define "allostasis" and "allostatic load" and give examples of each for the metabolic, cardiovascular and immune systems
  • Describe the role of excitatory amino acids (EAA) in relation to structural remodeling under stress and how this changes as the brain ages
  • Describe how glucocorticoids and EAA interact in relation to damage produced by ischemic and seizures on brain structures like the hippocampus
  • Describe why chronic stress may increase or decease vulnerability to insults such as ischemia or seizures.

This conference may include discussion of commercial products and services.

The opinions expressed herein are those of the authors and do not necessarily represent the views of the sponsor or its publisher. Please review complete prescribing information of specific drugs or combination of drugs, including indications, contraindications, warnings and adverse effects before administering pharmacologic therapy to patients.
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